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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC24A2
All Species:
10
Human Site:
S440
Identified Species:
18.33
UniProt:
Q9UI40
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI40
NP_065077.1
661
73664
S440
P
V
Q
N
G
N
L
S
H
N
I
E
G
A
E
Chimpanzee
Pan troglodytes
XP_528551
661
73638
S440
P
V
Q
N
G
N
L
S
H
N
I
E
G
A
E
Rhesus Macaque
Macaca mulatta
XP_001108751
661
73840
S440
P
V
Q
N
G
N
L
S
H
N
I
E
G
A
E
Dog
Lupus familis
XP_852036
664
74187
I443
N
G
N
L
S
H
T
I
E
A
A
E
A
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGQ8
605
66848
F394
P
E
S
V
E
T
V
F
L
S
P
F
S
M
P
Rat
Rattus norvegicus
O54701
670
74638
E449
G
N
L
S
H
S
I
E
A
A
D
A
P
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514353
346
38802
G136
A
V
I
L
H
V
F
G
M
I
Y
M
F
V
A
Chicken
Gallus gallus
Q9IAL7
651
72677
Q430
P
S
D
S
G
P
V
Q
N
G
I
A
H
N
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q49SH1
513
56764
S302
L
H
G
L
N
E
I
S
D
E
H
K
S
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6A0
888
95868
G670
T
L
A
D
R
P
N
G
N
I
D
T
T
L
D
Honey Bee
Apis mellifera
XP_396230
658
71609
A440
E
T
T
L
Q
N
R
A
F
G
I
D
V
L
L
Nematode Worm
Caenorhab. elegans
NP_001040663
596
66359
D386
E
Q
E
E
K
P
L
D
M
T
W
P
E
T
W
Sea Urchin
Strong. purpuratus
XP_787540
651
70927
E430
A
G
A
M
H
D
V
E
S
P
E
S
T
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.1
93.2
N.A.
35.2
88.6
N.A.
39.3
77
N.A.
31
N.A.
38.9
46.9
42.2
39.4
Protein Similarity:
100
99.8
98.6
95.3
N.A.
53.5
93.4
N.A.
44.9
86.8
N.A.
50.3
N.A.
53.2
61.2
60.3
53.8
P-Site Identity:
100
100
100
6.6
N.A.
6.6
0
N.A.
6.6
20
N.A.
6.6
N.A.
0
13.3
6.6
0
P-Site Similarity:
100
100
100
13.3
N.A.
20
20
N.A.
6.6
40
N.A.
20
N.A.
26.6
26.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
16
0
0
0
0
8
8
16
8
16
8
24
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
0
8
8
0
16
8
0
0
8
% D
% Glu:
16
8
8
8
8
8
0
16
8
8
8
31
8
8
24
% E
% Phe:
0
0
0
0
0
0
8
8
8
0
0
8
8
0
8
% F
% Gly:
8
16
8
0
31
0
0
16
0
16
0
0
24
0
0
% G
% His:
0
8
0
0
24
8
0
0
24
0
8
0
8
0
0
% H
% Ile:
0
0
8
0
0
0
16
8
0
16
39
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
8
8
31
0
0
31
0
8
0
0
0
0
16
8
% L
% Met:
0
0
0
8
0
0
0
0
16
0
0
8
0
8
0
% M
% Asn:
8
8
8
24
8
31
8
0
16
24
0
0
0
8
0
% N
% Pro:
39
0
0
0
0
24
0
0
0
8
8
8
8
0
8
% P
% Gln:
0
8
24
0
8
0
0
8
0
0
0
0
0
16
8
% Q
% Arg:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
16
8
8
0
31
8
8
0
8
16
0
0
% S
% Thr:
8
8
8
0
0
8
8
0
0
8
0
8
16
8
8
% T
% Val:
0
31
0
8
0
8
24
0
0
0
0
0
8
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _